Description
Composition:
Chlorhexidine gluconate solution I.P. equivalent to chlorhexidine gluconate 1.0% w/w in pleasantly flavoured base.
The use of Chlorhexidine gel:
The application of chlorhexidine (CHX) gel on ulcers and wound surfaces after oral surgical procedures has received considerable attention— supported scientifically by the antimicrobial properties of chlorhexidine.
Chlorhexidine acts against bacteria (Gram-positive and Gram-negative), with bacteriostatic action at low concentrations and bactericidal action at high concentrations Chlorhexidine is also known for its antiviral and antifungal effects.
Mode of action:
Chlorhexidine acts on the target micro-organisms by increasing their cell membrane permeability which causes the precipitation of cytoplasmic macromolecules and subsequent microbial death via cell lysis. Therefore, the effect of CHX is mainly based on minimizing the microbial load —playing an anti-infection role, which seems critical in the early stages of wound healing.
Indications:
1. Periodontal diseases: gingivitis, periodontitis
2. Oral candidiasis, esp denture stomatitis
3. Aphthous and other oral ulcers, such as due to dentures
4. Common oral injuries, including those from orthodontic appliances and oral surgery appliances
5. Maintenance of oral hygiene, especially interdentally — in cancer patients, gingivitis & periodontitis patients, between and around restorations
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